The changing clinical pattern of Reye ' s syndrome 1982 - 1990
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چکیده
*Deceased. Abstract Objective-To describe trends in the clinical pattern of Reye's syndrome in the British Isles between 1982 and 1990; and to determine the relation between any changes and the June 1986 warnings against the use ofaspirin in children. Design-Development, and application to reported cases, of a scoring system designed such that patients showing the typical clinical and pathological features of 'classical' Reye's syndrome scored highly. The relations between 'Reye scores' and a number of explanatory variables were explored using multivariable analysis. Setting-British Isles. Subjects-445 cases fulfilling the Reye's syndrome case definition reported to the surveillance scheme between January 1982 and December 1990. Main outcome measure-Individual 'Reye score'. Results-Cases with high scores were
منابع مشابه
The changing clinical pattern of Reye's syndrome 1982-90.
OBJECTIVE To describe trends in the clinical pattern of Reye's syndrome in the British Isles between 1982 and 1990; and to determine the relation between any changes and the June 1986 warnings against the use of aspirin in children. DESIGN Development, and application to reported cases, of a scoring system designed such that patients showing the typical clinical and pathological features of '...
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